Tuesday, January 10, 2017

What is Big data analytics

Big data analytics is the process of examining large data sets to uncover hidden patterns, unknown correlations, market trends, customer preferences and other useful business information. The analytical findings can lead to more effective marketing, new revenue opportunities, better customer service, improved operational efficiency, competitive advantages over rival organizations and other business benefits.
The primary goal of big data analytics is to help companies make more informed business decisions by enabling data scientists, predictive modelers and other analytics professionals to analyze large volumes of transaction data, as well as other forms of data that may be untapped by conventional business intelligence (BI) programs. That could include Web server logs and Internet clickstream data, social media content and social network activity reports, text from customer emails and survey responses, mobile-phone call detail records and machine data captured by sensors connected to the Internet of Things.

Semi-structured and unstructured data may not fit well in traditional data warehouses based on relational databases. Furthermore, data warehouses may not be able to handle the processing demands posed by sets of big data that need to be updated frequently or even continually -- for example, real-time data on the performance of mobile applications or of oil and gas pipelines. As a result, many organizations looking to collect, process and analyze big data have turned to a newer class of technologies that includes Hadoop and related tools such as YARN, MapReduce, Spark, Hive and Pig as well as NoSQL databases. Those technologies form the core of an open source software framework that supports the processing of large and diverse data sets across clustered systems.

12 Ways to Conquer 2017 New Years Resolutions

This new year everything will change. I'm going to do better on my diet, lose 100 pounds, stop smoking, walk and exercise more, get that cholesterol level down, stop drinking so much, be nicer to people, and blah, blah, blah.

We've all been there one year or another, wanting to make changes, sometimes we do, for a couple weeks, and then we relapse right back to where we were before the New Year. Then disappointed, we may try a mid February 'resolution' or mid year resolution, anything to get us motivated to make that change.

The question is why we wait for the New Year to come around to make it happen. We don't need to give it a name, or wait for a particular time of the year, we need to "just do it". If there is one thing that I've learned its that people really do not like change.

We get into our own little bubble, and we are in our 'zone' our comfort 'zone'. That is where we feel safe, it's not perfect, but hey, it's what we've always done and we are familiar with it and good or bad, we own it. We deeply resent others telling us that it's not healthy, that change is good.

The truth is, life is always changing. Life is a series of little steps moving us forward. Most people don't like change, but truly life is in a constant state of evolving. Always moving forward whether we are prepared or not. Change happens.

Some people hate change and resist it daily, generally those who do resist are suffering because they know that their resistance is in vain, change will happen whether you like it and accept it, or hate it and continue to resist. If you doubt this look in the mirror, you've changed since last year, and the year before. Life evolves without your permission or approval.

Obviously, the only way to stop change is to die, but wait that's the biggest change of all. Maybe tiny incremental changes are not so bad after all. Each single day and every single hour presents you with changes. Regardless of our acceptance or denial we are constantly changing, evolving, growing, and expanding.

So if change is a common daily occurrence, one which happens to all of us, regardless of our desire to accept it, why not make choices for our changes?

Move into the direction of change without fear, without resistance to it and most importantly move into change with purpose, passion, and focused intent, with a solid idea of your direction and goal.

1. Clarify your goal in writing, be exact. This is your destination.

2. Pick a date in the future. (Doesn't have to be New Years day.)

3. Give yourself a couple of weeks to think it over, become familiar with the idea that things are going to be better (usually healthier).

4. Write down your plan; focus on those daily steps to be successful. This is your road map.

5. Be reasonable. Don't set yourself up for failure. Be kind to yourself.

6. Make it measurable, be able to gauge how you're doing.

7. Set smaller goals to measure incremental steps (How to eat an elephant? One bite at a time.)

8. Give yourself a reward for when you accomplish you goal. Make it good!

9. Some people enjoy having a goal partner, someone who is going on the same path, but you will have to decide for yourself if this is best for you.

10. Most importantly: Take five minutes morning and night, to close your eyes and visualize yourself already experiencing your goal, feel it, see it, be it. Imagine being right there, where you want to be, having already reached your goal.

11. If you mess up one time, just get right back on the plan! You don't fail until you quit!

12. Congratulate yourself and set your next big goal!

Monday, January 9, 2017

Naruto episode 488 Latest episode: The Last One

"The Last One" (最後の一人, Saigo no Hitori) is episode 488 of the Naruto: Shippūden anime.

Chino confirms to Sasuke she intended to use the exploding humans to attack him and Konoha in vengeance against the Uchiha for driving her clan to the Valley of Hell, but ended up meeting him in the Bamboo Village. Her plans changed after Iō last words put Sasuke on Fūshin's track. Chino explains the Chinoike clan's jutsu uses blood, and that with the high iron content of the lake in the Valley of Hell, she'll be even more powerful. She uses her blood and the lake to create a multi-headed blood dragon, but Sasuke quickly decapitates all of its heads with his electrified sword. Chino manages to wound Sasuke, and as his wound closes, she uses the Ketsuryūgan to show him himself turning into an exploding human. Sasuke asks her if that's how she creates them, and Chino realises she's under the Sharingan's genjutsu, Sasuke standing on her blood dragon, which collapses. Chino envied Sasuke because he always had someone to love him, while she was alone from the start, which reminds Sasuke of Naruto and Sakura. Chino asks Sasuke why he still fights for Konoha, and he tells her about Naruto. Chino isn't convinced the world they want to bring about can be a reality, and tells Sasuke to kill her. Fūshin arrives, in bad shape, and tells Sasuke he'll have to kill him to get to Chino. Sasuke tells Chino his words to her should make sense now. Chino asks Fūshin not to fight, as she couldn't bear losing him. Chino wishes she hadn't met him in the Bamboo Village, so she could still hate him, and wishes to see the world Sasuke spoke of. In Konoha, guided by Hinata's Byakugan, Sakura finishes extracting the chakra infecting the exploding humans. They talk about the apprehension of the perpetrators, and how Sasuke wasn't there when they thought he would be. In prison, Kakashi meets Chino, Fūshin and Karyū, and Chino claims responsibility for the incident. Kakashi tells them the Mizukage wants to take custody of them. Mei arrives with Chōjūrō, and aware of their past connection with the village, wants them to help Kirigakure, as a form of atonement. At the Coliseum, Sasuke challenges all the shinobi, to earn them all their freedom. Chino is concerned about him fighting so many shinobi with kekkei genkai, but Naruto assures her Sasuke will win. After defeating all the shinobi, Futsu asks Sasuke what will happen to them. He says Kumogakure will take them in. The Raikage arrives with C, Darui, and several other shinobi. As the island of the Coliseum is nearest to Kumogakure, Kakashi argued with the Raikage they're his responsibility, as well as arresting all the Coliseum's patrons. A tells Sasuke about the time Naruto begged him not to kill him, and how he's glad he didn't. En Oyashiro meets up with Orochimaru, having escaped arrest. They discuss the Chinoike clan, En Oyashiro revealing himself to have the Ketsuryūgan, to be Chino's father, and to have killed the clan. Naruto and Sakura discuss Sasuke. Sasuke receives a message from Naruto by hawk, where Naruto says Sasuke protecting the village is like he's from the Konoha Police Force, which sparks in Sasuke a memory from talking with Itachi about wanting to join. Sasuke thinks maybe it's time to visit Konoha.

Thursday, January 5, 2017

Top 10 English songs 2016

Top 10 Songs of 2016
The Chainsmokers Featuring Halsey
One Dance
Drake Featuring WizKid & Kyla
Justin Timberlake
The Weeknd Featuring Daft Punk
Don't Let Me Down
The Chainsmokers Featuring Daya
This Is What You Came For
Calvin Harris Featuring Rihanna
7 Years
Lukas Graham
Stressed Out
twenty one pilots
twenty one pilots
Cheap Thrills
Sia Featuring Sean Paul

Thursday, December 30, 2010

Care your dreams

Its amazing how a small kid can dream of fairy and angels so easily. But once you get so called, "grown up" things change.Things you once like start losing their very existence. You need to work hard to earn hard, Make more money so you can live a better life; it's like to go round and round like a dog chasing its own tail and you know it better what he gets ...

Live your life it comes only once, don't just have your dreams live it. You should not regret that you could have but didn't.

Wednesday, May 21, 2008

Is Mars Between Ice Ages?

"Mars is not a dead planet -it undergoes climate changes that are even more pronounced than on Earth."
James Head of Brown University
The prevailing thinking is that Mars is a planet whose active climate has been confined to the distant past. About 3.5 billion years ago, the Red Planet had extensive flowing water and then fell quiet - deadly quiet. It didn't seem the climate had changed much since. Now, recent studies by scientists at Brown University show that Mars' climate has been much more dynamic than previously believed.
After examining stunning high-resolution images taken last year by the Mars Reconnaissance Orbiter, researchers have documented for the first time that ice packs at least 1 kilometer (0.6 miles) thick and perhaps 2.5 kilometers (1.6 miles) thick existed along Mars' mid-latitude belt as recently as 100 million years ago. In addition, the team believes other images tell them that glaciers flowed in localized areas in the last 10 to 100 million years - a blink of the eye in Mars's geological timeline.This evidence of recent activity means the Martian climate may change again and could bolster speculation about whether the Red Planet can, or did, support life."We've gone from seeing Mars as a dead planet for three-plus billion years to one that has been alive in recent times," said Jay Dickson, a research analyst in the Department of Geological Sciences at Brown and lead author. "[The finding] has changed our perspective from a planet that has been dry and dead to one that is icy and active."In fact, Dickson and his co-authors, James Head, a planetary geologist, and David Marchant, an associate professor at Boston University, believe the images show that Mars has gone through multiple Ice Ages - episodes in its recent past in which the planet's mid-latitudes were covered by glaciers that disappeared with changes in the Red Planet's obliquity, which changes the climate by altering the amount of sunlight falling on different areas.
NASA's Mars Global Surveyor and Mars Odyssey missions have provided evidence of a relatively recent ice age on Mars. In contrast to Earth's ice ages, a Martian ice age expands when the poles warm, and water vapor is transported toward lower latitudes. Martian ice ages wane when the poles cool and lock water into polar icecaps.The catalysts of ice ages on Mars appear to be much more extreme than the comparable drivers of climate change on Earth. Variations in the planet's orbit and tilt produce remarkable changes in the distribution of water ice from Polar Regions down to latitudes equivalent to Houston or Egypt. Researchers, using NASA spacecraft data and analogies to Earth's Antarctic Dry Valleys, reported their findings in the journal Nature."Of all the solar system planets, Mars has the climate most like that of Earth. Both are sensitive to small changes in orbital parameters," said planetary scientist Dr. James Head of Brown University. "Now we're seeing that Mars, like Earth, is in a period between ice ages," he said. This evidence of recent activity means the Martian climate may change again and could bolster speculation about whether the Red Planet can, or did, support life.Head and his team examined global patterns of landscape shapes and near-surface water ice Nasa's Mars orbiters mapped. They concluded a covering of water ice mixed with dust mantled the surface of Mars to latitudes as low as 30 degrees, and is degrading and retreating. By observing the small number of impact craters in those features and by backtracking the known patterns of changes in Mars' orbit and tilt, they estimated the most recent ice age occurred just 400 thousand to 2.1 million years ago.
Marchant, a glacial geologist who spent 17 field seasons in the Mars-like Antarctic Dry Valleys, said, "These extreme changes on Mars provide perspective for interpreting what we see on Earth. Landforms on Mars that appear to be related to climate changes help us calibrate and understand similar landforms on Earth. Furthermore, the range of microenvironments in the Antarctic Dry Valleys helps us read the Mars record."According to the researchers, during a Martian ice age, polar warming drives water vapor from polar ice into the atmosphere. The water comes back to ground at lower latitudes as deposits of frost or snow mixed generously with dust. This ice-rich mantle, a few meters thick, smooths the contours of the land. It locally develops a bumpy texture at human scales, resembling the surface of a basketball, and also seen in some Antarctic icy terrains. When ice at the top of the mantling layer sublimes back into the atmosphere, it leaves behind dust, which forms an insulating layer over remaining ice. On Earth, by contrast, ice ages are periods of polar cooling. The buildup of ice sheets draws water from liquid-water oceans, which Mars lacks.
Dickson and the other researchers focused on an area called Protonilus Mensae-Coloe Fossae. The region is located in Mars's mid-latitude and is marked by splotches of mesas, massifs and steep-walled valleys that separate the lowlands in the north from the highlands in the south.
The team looked in particular at a box canyon set in a low-lying plain. Images show the canyon has moraines - deposits of rocks that mark the limits of a glacier's advance or the path of its retreat. The rock deposit lines appear to show a glacier that flowed up the box canyon, which "physically cannot happen," Dickson said.Instead, the team deduced the ice in the surrounding plain grew higher than the canyon's walls and then flowed downward onto the top of the canyon, which had become the lowest point on the ice-laden terrain. The team calculated the ice pack must have been one kilometer thick by past measurements of height between the plain and the lip of the canyon. Based on the ice flow patterns, the ice pack could have reached 2.5 kilometers at peak thickness during a period known as the late Amazonian, the authors said.The finding could have implications for the life-on-Mars argument by strengthening the case for liquid water. Ice can melt two ways: by temperature or by pressure. As currently understood, the Martian climate is dominated by sublimation, the process by which solid substances are transformed directly to vapor. But ice packs can exert such strong pressure at the base to produce liquid water, which makes the thickness of past glaciers on its surface so intriguing.Dickson also looked at a lobe across the valley from the box canyon site. There, he saw a clear, semi-circular moraine that had spilled from an ancient tributary on to the surrounding plain. The lobe is superimposed on a past ice deposit and appears to be evidence of more recent glaciation. Although geologists can't date either event, the landscape appears to show at least two periods in which glaciation occurred, bolstering their theory that the Martian climate has undergone past Ice Ages.
Posted by Casey Kazan.
Related Galaxy posts:
Unraveling the Mysteries of Mars -Clues to Climate Change on Earth?Movie of NASA's Sites on Mars for Future Landings & Search for Ancient LifeMars Exploration: Secrets of the SoilIs There Life on Mars? NASA Goes Underground to Find OutNew Phoenix Mission Technology to Search for Mars LifeIs there an Interplanetary Mars-Earth Microbe Shuttle?"The Overview Effect": Is Space Travel Next Step in Human Evolution?Lonely Hearts of the Cosmos Revisited -NASA's Phoenix Probe & the Search for Extraterrestrial LifePhoenix Lander and the 'Canals' of Mars

Saturday, April 12, 2008

Nanoparticles hitchhike on red blood cells for drug delivery

By Society for Experimental Biology and Medicine, [RxPG] Researchers at the University of California, Santa Barbara have discovered that attaching polymeric nanoparticles to the surface of red blood cells dramatically increases the in vivo lifetime of the nanoparticles. The research, published in the July 07 issue of Experimental Biology and Medicine, could offer applications for the delivery of drugs and circulating bioreactors.Polymeric nanoparticles are excellent carriers for delivering drugs. They protect drugs from degradation until they reach their target and provide sustained release of drugs. Polymeric nanoparticles, however, suffer from one major limitation: they are quickly removed from the blood, sometimes in minutes, rendering them ineffective in delivering drugs.The research team, led by Samir Mitragotri, a professor of chemical engineering, and Elizabeth Chambers, a recent doctoral graduate, found that nanoparticles can be forced to remain in the circulation when attached to red blood cells. The particles eventually detach from the blood cells due to shear forces and cell-to-cell interactions, and are cleared from the system by the liver and spleen. Red blood cell circulation is not affected by attaching the nanoparticles."Attachment of polymeric nanoparticles to red blood cells combines the advantages of the long circulating lifetime of the red blood cell, and their abundance, with the robustness of polymeric nanoparticles," said Mitragotri. "Using red blood cells to extend the circulation time of the particles avoids the need to modify the surface chemistry of the entire particle, which offers the potential to attach chemicals to the exposed surface for targeting applications."The researchers have learned that particles adhered to red blood cells can escape phagocytosis because red blood cells have a knack for evading macrophages. Nanoparticles aren't the first to be piggybacking on red blood cells; the strategy has already been adopted by certain bacteria, such as hemobartonella, that adhere to RBCs and can remain in circulation for several weeks. The researchers say that it may be possible to keep the nanoparticles in circulation for a relatively long time, theoretically up to the circulation lifetime of a red blood cell - which is 120 days - if the binding between particles and the red blood cells is strengthened. The methodology is applicable to drugs that are effective while still attached to a red blood cell, although the researchers say that slow release from the red blood cell surface is also feasible.Mitragotri says "this mode of prolonging particle circulation has significant implications in drug delivery, potentially leading to new treatments for a broad variety of conditions such as cancer, blood clots and heart disease". Dr. Steven R. Goodman, Editor-in-Chief of the journal, said "this study dealing with the attachment of nanoparticles to red blood cells may also have important implications for future treatment of hematologic disorders. This fusion of modern nanobioscience with cell biology and hematology is precisely the type of interdisciplinary study that the new Experimental Biology and Medicine is interested in publishing."
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